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University of Louisville Bioinformatics

Bioinformatics Research at the University of Louisville


rMotifGen: Random Motif Sequence Generator for Genomic Sequences


Eric C. Rouchka(1,2) C. Timothy Hardin(1,2)

  1. University of Louisville Department of Computer Engineering and Computer Science.
  2. University of Louisville Department of Bioinformatics Research Group.
rMotifGen is a solution with the sole purpose of generating a number of random DNA or amino acid sequences containing short sequence motifs. Each motif consensus can be either user-defined, or randomly generated. Insertions and mutations within these motifs are created according to user-defined parameters. The resulting sequences can be helpful in mutational simulations and in testing the limits of motif detection algorithms.

rMotifGen is available as a C# interface for windows users and as a C++ command line interface.


VERSION 2.0 (DNA and Amino Acids)

  • C++ Tar file rMotifGen2.0.tar.gz
  • C# Graphical User Interface rMotifGen_2.0.exe

    VERSION 1.0 (DNA only)

  • Citations:
    Rouchka EC, Hardin CT (2007). rMotifGen: random motif generator for DNA and protein sequences. BMC Bioinformatics, 8:292. (doi:10.1186/1471-2105-8-292).

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