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University of Louisville Bioinformatics

Bioinformatics Research at the University of Louisville


Project:

rMotifGen: Random Motif Sequence Generator for Genomic Sequences


Authors:

Eric C. Rouchka(1,2) C. Timothy Hardin(1,2)

  1. University of Louisville Department of Computer Engineering and Computer Science.
  2. University of Louisville Department of Bioinformatics Research Group.
Motivation:
rMotifGen is a solution with the sole purpose of generating a number of random DNA or amino acid sequences containing short sequence motifs. Each motif consensus can be either user-defined, or randomly generated. Insertions and mutations within these motifs are created according to user-defined parameters. The resulting sequences can be helpful in mutational simulations and in testing the limits of motif detection algorithms.

 
Results:
rMotifGen is available as a C# interface for windows users and as a C++ command line interface.

LATEST VERSION (Adds PSSMs)

VERSION 2.0 (DNA and Amino Acids)

  • C++ Tar file rMotifGen2.0.tar.gz
  • C# Graphical User Interface rMotifGen_2.0.exe

    VERSION 1.0 (DNA only)

  • Citations:
    Rouchka EC, Hardin CT (2007). rMotifGen: random motif generator for DNA and protein sequences. BMC Bioinformatics, 8:292. (doi:10.1186/1471-2105-8-292).


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